Manchester United came from a goal down to defeat nine-man Fulham and reach the FA Cup semi-finals with a controversial victory at Old Trafford.
The Cottagers looked on course for only their second last-four appearance since they lost to West Ham in the 1975 final when their world collapsed with a Willian handball incident 15 minutes from time after Mitrovic had headed them in the lead in the 5oth minute.
Jadon Sancho seemed to be shooting an equaliser into an empty net, only for Brazilian winger Willian to charge across and clear.
Referee Chris Kavanagh initially gave a corner, but VAR advised the official to check the pitchside monitor, with Willian protesting and manager Marco Silva furious.
Silva was red carded for his touchline protests before Kavanagh could even reach a decision. Willian was dismissed after the check which resulted in Aleksander Mitrovic grabbing the referee as he angrily remonstrated and became the third man to be sent off.
Once order was restored, Bruno Fernandes tucked home the penalty.
In the space of two minutes, Fulham had lost two men, their manager and the lead.
Two minutes later, Marcel Sabitzer turned home Luke Shaw’s cross to make it 2-1 to United before Fernandes added an injury-time third off a Fred pass to knock Fulham out of the FA Cup.
The Red Devils will now play Brighton in the semi-final at Wembley with neighbors Manchester City facing Sheffield United who came from behind to defeat Blackburn.